FIELD: medicine, pharmaceutics.
SUBSTANCE: given invention refers to drugs containing compounds of specified structural formulae or to their pharmaceutically acceptable salts. Besides, the invention refers to pharmaceutical compositions for treating a host infected by hepatitis B virus, on the basis of each of said compounds separately (or their pharmaceutically acceptable salt), and also in their combination with an effective amount of a compound chosen from a group consisting of β-L-2-hydroxymethyl-5-(cytosine-1-yl)-1,3-oxathiolane (3TC), cys-2-hydroxymethyl-5-(5-fluorocytosine-5-yl)-1,3-oxathiolane (FTC), β-L-2'-fluor-5-methyl-arabinofuranosyl-uridine (L-FMAU), β-D-2,6-diaminopurindioxolane (DAPD), famciclovir, penciclovir, 2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)2-methylenecyclopentyl]-6H-purine-6-one (entecavir, BMS-200475), 9-[2-(phosphono-methoxy)ethyl]adenine (PMEA, adefovir, dipivoxyl), lobucavir, ganciclovir and ribavirin.
.
EFFECT: creation of the drug for treating a host infected by hepatitis B virus.
12 cl, 6 tbl, 4 dwg, 11 ex
| Title | Year | Author | Number |
|---|---|---|---|
| β-L-2'-DEOXYNUCLEOSIDES USED IN HEPATITIS B TREATMENT | 1999 |
|
RU2300381C2 |
| NUCLEOSIDES WITH ACTIVITY AGAINST HEPATITIS B VIRUS | 1999 |
|
RU2237479C2 |
| MONOCYCLIC L-NUCLEOSIDES, THEIR ANALOGUES AND USING | 1997 |
|
RU2188828C2 |
| NUCLEOTIDES INCLUDING N-[(S)-1-CYCLOBUTOXYCARBONYL]PHOSPHORAMIDATE FRAGMENT, THEIR ANALOGS AND THEIR APPLICATION | 2017 |
|
RU2659388C1 |
| CYCLOBUTYL (S)-2-[[[R)-2-(6-AMINOPURIN-9-YL)-1-METHYL-ETOXY]METHYL-PHENOXY-PHOSPHORYL]AMINO]-PROPANOATES, METHOD OF THEIR PRODUCTION AND APPLICATION | 2017 |
|
RU2647576C1 |
| ANTIVIRAL COMPOSITION AND METHOD OF ITS APPLICATION | 2017 |
|
RU2650610C1 |
| METHODS OF PRODUCING 2'-FLUORO-2'-ALKYL-SUBSTITUTED OR OTHER SUBSTITUTED RIBOFURANOSYL PYRIMIDINES AND PURINES AND DERIVATIVES THEREOF | 2005 |
|
RU2433124C2 |
| 2'-AMINO-2'-DEOXYNUCLEOSIDES AS INHIBITORS IF MEASLES AND MARBURG VIRUSUS REPRODUCTION | 2003 |
|
RU2264409C2 |
| COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING VIRAL INFECTIONS | 2007 |
|
RU2525392C2 |
| COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING VIRAL INFECTIONS | 2007 |
|
RU2466729C2 |
