FIELD: chemistry.
SUBSTANCE: present invention relates to methods of producing derivatives of 2'-deoxy, 2'-fluoro-2'-methyl-D-ribonolactone 
from starting compounds 
or 
.
EFFECT: obtained derivatives of 2'-deoxy, 2'-fluoro-2'-methyl-D-ribonolactone can be used to produce nucleosides containing 2'-deoxy-2'-fluoro-2'-C-methyl-β-D-ribofuranosyl nucleosides and having strong anti-HCV activity.
8 cl, 22 ex
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|---|---|---|---|
| METHOD OF PRODUCING ALKYL-SUBSTITUTED 2-DESOXY-2-FLUORO-D-RIBOFURANOSYL-PYRIMIDINES AND PURINES AND DERIVATIVES THEREOF | 2005 |
|
RU2407747C2 |
| β-D-2ʹ-DEOXY-2ʹ-α-FLUORO-2ʹ-β-C-SUBSTITUTED-2-MODIFIED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR TREATMENT OF DISEASES CAUSED BY HCV | 2016 |
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| MONOCYCLIC L-NUCLEOSIDES, THEIR ANALOGUES AND USING | 1997 |
|
RU2188828C2 |
| SYNTHESIS OF β-L-2'-DESOXYNUCLEOSIDES | 2004 |
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| METHOD OF SYNTHESIS OF 2',3'-DIDEOXY-3'-THIACYTYDINE OR 2',3'- -DIDEOXY-3'-THIA-5-FLUOROCYTIDINE, NUCLEOSIDE ENRICHED WITH ENANTIOMER, METHOD OF SYNTHESIS OF 1,3-OXATHIOLANE, METHOD OF SYNTHESIS OF 2-ACYLOXY-5-ACYLOXY-1,3-OXATHIOLANE ENRICHED WITH ENANTIOMER, ENANTIOMERS, METHOD OF CLEAVAGE OF NUCLEOSIDE ENANTIOMERS | 1991 |
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| METHOD OF OBTAINING 2'-DESOXY-2', 2'-DIFLUOROCYTIDINE | 2005 |
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RU2360919C2 |
| METHOD OF SYNTHESIS OF 2'-DEOXY-2'-FLUORORIBONUCLEOSIDE DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS | 1990 |
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RU2043361C1 |
| β-L-2' DEOXY-NUCLEOSIDES FOR TREATING HEPATITIS B | 1999 |
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