EFFICIENT HEMOSTATIC MEDICATION BASED ON LITHIUM AND DOUBLE LITHIUM-ZINC SALT OF POLYACRYLIC ACID Russian patent published in 2011 - IPC A61K31/78 A61P7/04 C08F8/42 

FIELD: medicine, pharmaceutics.

SUBSTANCE: claimed invention relates to creation of novel chemical compounds, which can be used in medicine as hemostatic medications of local action. Described in incomplete lithium salt of polyacrylic acid (liacryl), which is characterised by correespondance to formula: (-CH₂-CHCOOH-)_n(-CH₂CHCOOLi-)_m, where n=13496-28570; m=1672-4499, content of lithium constituting 6-8 wt % (0.0011-0.0012 g-at), and content of carboxyl groups constitutes 0.0118-0.0121 g-equiv per 1 g of polymer, molecular weight is 1000000-3000000. Also described is incomplete double lithium-zinc salt of polyacrylic acid (licicryl), corresponding to general formula: (-CH₂CHCOOH-)_n(-CH₂CHCOOLi-)_m(-CH₂CHCOOZn-)_k, where n=13777-18255; m=4227-4679, k=1666-2180, total content of metals constitutes 6-8 wt % (0.0010-0.0011 g-at), content of carboxyl groups constitutes 0.0117-0.0120 g-equiv, molecular weight is 1000000-3000000. Described are methods of obtaining said above incomplete salts of polyacrylic acid. Also described is medication, possessing efficient hemostatic action in external application, which contains said above incomplete lithium salt of polyacrylic acid, characterised by the fact that it is made in form of solutions with ratio 1-10 g of principal substance per 100 ml of water (1-10%). Described is medication, which possesses efficient hemostatic and expressed antiseptic action in external application, which contain said above incomplete lithium-zinc salt, characterised by the fact that it is made in form of solution with ratio 2-5 g of principal substance per 100 ml of water (2-5%).

EFFECT: obtaining novel chemical compounds, which can be used in medicine as hemostatic medication of local action, possessing high hemostatic effect.

6 cl, 1 tbl, 7 ex