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IPC

A61K31/78(2006-01-01)

A61K31/315(2006-01-01)

A61P17/02(2006-01-01)

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Application

2006118020/15, 2006-05-25

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Start date

2006-05-25

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Actual filing date

2006-05-25

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Published

2008-01-20

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Inventor

Abzaeva Klavdija AlsykovnaVoronkov Mikhail Grigor'EvichZhilitskaja Larisa VladimirovnaFedorin Andrej Jur'EvichMakarov Vladimir AleksandrovichBelozerskaja Galina Gennad'EvnaZhidkov Evgenij AleksandrovichFadeeva Tat'Jana VladimirovnaKogan Aleksandr SemenovichGrigor'Ev Evgenij Georgievich

(73)

Holder

Irkutskij Institut Khimii Im. A.E. Favorskogo Sibirskogo Otdelenija Rossijskoj Akademii Nauk So Ran)Gosudarstvennoe Uchrezhdenie Gematologicheskij Nauchnyj Tsentr Rossijskoj Akademii Meditsinskikh Nauk Gnts Ramn)Gosudarstvennoe Uchrezhdenie Nauchnyj Tsentr Rekonstruktivnoj I Vosstanovitel'Noj Khirurgii Vostochno-Sibirskogo Nauchnogo Tsentra Sibirskogo Otdelenija Rossijskoj Akademii Meditsinskikh Nauk Nts Rvkh Vsnts So Ramn)Obshchestvo S Ogranichennoj Otvetstvennost'Ju Innovatsionnaja Kompanija Grupp"

POLYACRYLIC ACID INCOMPLETE ZINC SALT, METHOD FOR ITS PREPARING AND AGENT BASED ON THEREOF POSSESSING ANTISEPTIC, HEMOSTATIC AND WOUND-HEALING EFFECT IN EXTERNAL USING Russian patent published in 2008 - IPC A61K31/78 A61K31/315 A61P17/02

Abstract RU 2314815 C1

FIELD: chemical-pharmaceutical industry, metalloorganic chemistry, medicine, pharmacy.

SUBSTANCE: invention relates to polyacrylic acid incomplete zinc salt corresponding to the formula: (-CH₂-CHCOOH-)_n(-CH₂CHCOOZn_0.5-)_m wherein n = 12000-35000; m = 1650-6650 wherein the content of zinc is (6-8 wt.-%) 0.0009-0.0012 g-at, the content of carboxyl groups is 0.0117-0.0122 g-equv/1 g of polymer, and molecular mass is in the limits 1000000-3000000 Da. Also, invention proposes a method for preparing this salt that involves addition of zinc acetate aqueous solution to polyacrylic acid solution, stirring the reaction mixture for 120-300 min and drying the prepared solution under vacuum at temperature 50°C, not above. Agent is prepared as a solution in the ratio 1-10 g of polyacrylic acid incomplete zinc salt in 100 ml of water. Agent shows antiseptic, hemostatic and wound-healing effect in its external using.

EFFECT: improved preparing method, valuable medicinal properties of agent.

3 cl, 1 tbl, 4 ex

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RU 2 314 815 C1

Authors

Abzaeva Klavdija Alsykovna

Voronkov Mikhail Grigor'Evich

Zhilitskaja Larisa Vladimirovna

Fedorin Andrej Jur'Evich

Makarov Vladimir Aleksandrovich

Belozerskaja Galina Gennad'Evna

Zhidkov Evgenij Aleksandrovich

Fadeeva Tat'Jana Vladimirovna

Kogan Aleksandr Semenovich

Grigor'Ev Evgenij Georgievich

Dates

2008-01-20—Published

2006-05-25—Filed