Show metadata Hide metadata

(19)

(11)

2 425 890

(13)

(51)

IPC

C12Q1/68(2006-01-01)

G01N33/50(2006-01-01)

C12N15/85(2006-01-01)

(21) (22)

Application

2009119219/10, 2009-05-21

(24)

Start date

2009-05-21

(22)

Actual filing date

2009-05-21

(45)

Published

2011-08-10

(72)

Inventor

Jurov Jurij BorisovichAleksandrov Ivan AleksandrovichSolov'Ev Il'Ja VladimirovichJurov Ivan Jur'EvichVorsanova Svetlana Grigor'Evna

(73)

Holder

Federal'Noe Gosudarstvennoe Uchrezhdenie Nauchno-Issledovatel'Skij Institut Pediatrii I Detskoj Khirurgii" Ministerstva Zdravookhranenija I Sotsial'Nogo Razvitija Rossijskoj Federatsii

METHOD OF MARKING HUMAN 7TH CHROMOSOME IN METAPHASIC AND INTERPHASIC CELLS Russian patent published in 2011 - IPC C12Q1/68 G01N33/50 C12N15/85

Abstract RU 2425890 C2

FIELD: medicine.

SUBSTANCE: what is offered is a method of marking a human 7th chromosome providing in situ hybridisation of metaphasic or interphasic cell chromosomes of a tested sample and a DNA probe presented by a marker plasmid alpha R1-13 which consists of EcoR 1-EcoR l DNA fragment of a pBR 325 vector of the value 5966 base pairs and EcoRl-EcoRl alphoid DNA fragment of the human 7th chromosome of the value 680 base pairs. The testing environment in which the used DNA-probe specifically interacts with a centromeric region of the 7th chromosome without cross hybridisation with other human chromosomes are developed.

EFFECT: more efficient identification of the presented chromosome and enabled application of the new method in medical diagnostics.

4 ex

Similar patents RU2425890C2

Title	Year	Author	Number
RECOMBINANT PLASMID DNA ALPHA-R-12 DESIGNATED FOR MARKING 6-TH HUMAN CHROMOSOME IN METAPHASE IN INTERPHASE CELLS	2004	Jurov Ju.B. Jakovlev A.G. Vorsanova S.G. Solov'Ev I.V.	RU2265060C1
RECOMBINANT PLASMID DNA pYAII-39, USED FOR 4TH AND 9TH HUMAN CHROMOSOME MARKING IN METAPHASIC AND INTERPHASIC CELLS	2006	Jurov Jurij Borisovich Aleksandrov Ivan Aleksandrovich Vorsanova Svetlana Grigor'Evna Solov'Ev Il'Ja Vladimirovich	RU2325441C1
RECOMBINANT PLASMID DNA ALPHA R 1-6 DESIGNATED FOR MARKING THE 13-TH AND 21-D HUMAN CHROMOSOMES	1995	Solov'Ev I.V. Jurov Ju.B. Vorsanova S.G. Jakovlev A.G. Demidova I.A.	RU2087534C1
RECOMBINANT PLASMID DNA PYAI 960 DESIGNATED FOR HUMAN 18-TH CHROMOSOME MARKING	2000	Jurov Ju.B. Vorsanova S.G. Aleksandrov I.A.	RU2161199C1
SET OF RECOMBINANT PLASMID DNA PYAI 11-19, PYAI 2-45, PYS 37 AND PYAI 7-29 FOR DETERMINATION OF ORIGIN OF HUMAN ACCESSORY OR MARKER (MINI-) CHROMOSOMES	2002	Jurov Ju.B. Solov'Ev I.V. Vorsanova S.G. Aleksandrov I.A. Demidova I.A.	RU2200761C1
RECOMBINANT PLASMID DNA PYAIA05 FOR MARKING AND IDENTIFICATION OF THE THIRD HUMAN CHROMOSOME	1994	Jurov Ju.B. Vorsanova S.G. Aleksandrov I.A.	RU2087533C1
RECOMBINANT PLASMID DNA ALPHA RI-7 FOR LABELLING OF THE FIRST HUMAN CHROMOSOME	0	Yurov Yurij Borisovich Vorsanova Svetlana Grigorevna Yakovlev Aleksandr Georgievich	SU1792429A3
METHOD OF LABELLING MANЪS 11TH CHROMOSOME,RECOMBINATION PLASMIDE OF GENOME DEOXYRIBONUCLEIC ACID PHS 53 FOR LABELLING AND METHOD OF PRODUCING FRAGMENT OF DEOXYRIBONUCLEIC ACID PHS 53	0	Gindilis Viktor Mironovich Zajtsev Igor Zakvanovich Yakovlev Aleksandr Georgievich Yurov Yurij Borisovich Shapiro Yurij Abramovich	SU1203108A1
METHOD OF DETERMINING QUANTITY OF X-CHROMOSOME OF MAN	0	Yurov Yu.B. Aleksandrov I.A. Mitkevich S.P. Vorsanova S.G.	SU1494724A1
DIAGNOSTIC TECHNIQUE FOR UROTHELIAL BLADDER CANCER	2011	Vorobtsova Irina Evgen'Evna Vasil'Eva Zaure Zhenisovna	RU2456607C1

RU 2 425 890 C2

Authors

Jurov Jurij Borisovich

Aleksandrov Ivan Aleksandrovich

Solov'Ev Il'Ja Vladimirovich

Jurov Ivan Jur'Evich

Vorsanova Svetlana Grigor'Evna

Dates

2011-08-10—Published

2009-05-21—Filed