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2 265 060

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IPC

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Application

2004103276/13, 2004-02-05

(24)

Start date

2004-02-05

(22)

Actual filing date

2004-02-05

(45)

Published

2005-11-27

(72)

Inventor

Jurov Ju.B.Jakovlev A.G.Vorsanova S.G.Solov'Ev I.V.

(73)

Holder

Moskovskij Nauchno-Issledovatel'Skij Institut Pediatrii I Detskoj Khirurgii Ministerstva Zdravookhranenija Rossijskoj Federatsii Uchrezhdenie Nauki)

RECOMBINANT PLASMID DNA ALPHA-R-12 DESIGNATED FOR MARKING 6-TH HUMAN CHROMOSOME IN METAPHASE IN INTERPHASE CELLS Russian patent published in 2005 - IPC

Abstract RU 2265060 C1

FIELD: genetic engineering, medicinal genetics.

SUBSTANCE: invention relates to the constructed plasmid DNA alpha-R-12 based on vector pBR325 and fragment of alphoidal DNA of human lymphocytes prepared from Eco RI restricts of the total fraction of human alphoidal DNA in hybridization on chromosomes in situ under special conditions of enhanced rigidity. Using the invention allows carrying out the reliable identification of human 6-th chromosome in norm and in pathology.

EFFECT: improved method for chromosome analysis.

4 ex

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RU 2 265 060 C1

Authors

Jurov Ju.B.

Jakovlev A.G.

Vorsanova S.G.

Solov'Ev I.V.

Dates

2005-11-27—Published

2004-02-05—Filed