FIELD: medicine, pharmaceutics.
SUBSTANCE: claimed is composition in form of one-layer, without cavities film, which does not contain surface-active substances, gas-generating additives and taste-masking agents and contains at least two film-generators, one or several gel-generators and as active substance from group of neuroleptics - olanzapine. Film-generating agents are selected from the following group: sugars, sugar alcohols and their derivatives, low-molecular organic acids, polyethylene glycol, polyethylene glycol dioleate, 1,3-butanediol, propylene glycol, glycerol, isopropyl palmitate, dibutyl sebacynate, paraffin oil and castor oil, ethylcellulose, cellulose acetate, cellulose phthalate and their mixtures. At least one film-generating agent is water-insoluble. Composition by invention is applied for preparation of medication intended for treatment of central nervous system disorders.
EFFECT: composition in form of film by invention is characterised by high mechanical strength and ability to release active substance quickly, during several seconds.
26 cl, 3 ex
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Authors
Dates
2011-08-27—Published
2006-07-20—Filed