UNSPITTABLE QUICKLY DECOMPOSING NEUROLEPTIC-CONTAINING FILM FOR ORAL APPLICATION Russian patent published in 2011 - IPC A61K31/551 A61K31/4515 A61K47/30 A61K47/26 A61K9/70 A61K9/22 A61P25/18 A61P25/00 

Abstract RU 2427374 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: claimed is composition in form of one-layer, without cavities film, which does not contain surface-active substances, gas-generating additives and taste-masking agents and contains at least two film-generators, one or several gel-generators and as active substance from group of neuroleptics - olanzapine. Film-generating agents are selected from the following group: sugars, sugar alcohols and their derivatives, low-molecular organic acids, polyethylene glycol, polyethylene glycol dioleate, 1,3-butanediol, propylene glycol, glycerol, isopropyl palmitate, dibutyl sebacynate, paraffin oil and castor oil, ethylcellulose, cellulose acetate, cellulose phthalate and their mixtures. At least one film-generating agent is water-insoluble. Composition by invention is applied for preparation of medication intended for treatment of central nervous system disorders.

EFFECT: composition in form of film by invention is characterised by high mechanical strength and ability to release active substance quickly, during several seconds.

26 cl, 3 ex

Similar patents RU2427374C2

Title Year Author Number
FILM-GENERATING COMPOSITION FOR APPLICATION OF COATINGS BASED ON SOLID POWDER-LIKE COMPOUNDS 2010
  • Tomas Durig
  • Dajvja Tevari
RU2563133C2
ORAL CARE AND ODOUR CONTROL COMPOSITIONS 2011
  • Bojd Tomas
  • Li Leonora
RU2543649C2
NEW PROLONGED COMPOSITIONS FOR PERORAL ADMINISTRATION 1999
  • Ogorka Jerg
  • Kal'B Oskar
  • Shakh Radzhen
  • Kanna Satish Chandra
RU2286766C2
CONTROLLED-RELEASE COMPOSITIONS FOR ORAL USING 2000
  • Shakh Radzhen
  • Kkhanna Satish Chandra
  • Kal'B Oskar
  • Ogorka Jerg
RU2281758C2
CONSUMED FILM FOR IN-MOUTH HOLDING AND A METHOD FOR PREPARATION OF CONSUMED FILM 2001
  • Bess Uill'Jam S.
  • Kulkarni Neema
  • Ehmbajk Sukhas Kh.
  • Rehmsehj Majkl Pol
RU2256442C2
COMPOSITION OF SOLID QUICK-DISINTEGRATING TABLET 2008
  • D'Jurig Tomas
RU2472493C2
PHARMACEUTICAL COMPOSITION INCLUDING DICLOFENAC 2005
  • Mejer Shtefan
  • Rol' Izabella
  • Shobel' Aleksander Mark
  • Slominski Greg
  • Spenser Gejvin Mjurrej
RU2424793C2
SOLID DOSAGE FORM 2004
  • Brauns Ul'Rikh
  • Fridl' Tomas
  • Landerer Zabine
RU2377987C2
FAST-DISINTEGRATING FOAMED PASTILLES WITH HIGH WEIGHT PER UNIT AREA 2018
  • Mueller, Markus
  • Bauer, Marius
  • Linn, Michael
RU2826556C1
POCKET-SHAPED ORAL SOLUBLE FILMS WITH HIGH ACTIVE SUBSTANCE LOAD 2018
  • Schmitz, Christoph
  • Bauer, Marius
RU2742415C1

RU 2 427 374 C2

Authors

Obermajer Petra

Kor Tomas

Kramer Kaj-Tomas

Klokkers Karin

Dates

2011-08-27Published

2006-07-20Filed