SOLID DOSAGE FORM Russian patent published in 2010 - IPC A61K31/46 A61K9/20 A61J3/10 A61P25/00 

FIELD: medicine.

SUBSTANCE: present invention refers to medical products, particularly to a solid dosage form, containing an active substance from the group of inhibitor monoamine neurotransmitter uptake inhibitors with 2 3-two-substituted tropane skeleton of formula (1) which is produced by spaying a solution of the active substance over the carrier and containing the following components: 0.01-5.00 wt % of the active substance, 80.00-95.00 wt % of one or more carriers chosen from the group including carbohydrates and binding agents, providing binding of the components in a dry state, 1.00-10.00 wt % of one or more adjuvants chosen from the group, including cellulose derivative and salts of fatty acids, 0-10.00 wt % of a film coating mainly containing one or more filming agents, one or more elasticity improving substances, one or more pigments and optionally one or more dyes. Besides the inventions concern the method for making said dosage form and application thereof.

EFFECT: said dosage form expresses improved uniformity of the active substance, stability and biocompatibility.

17 cl, 2 dwg, 6 tbl, 4 ex