FIELD: chemistry.
SUBSTANCE: method involves treating creatine with pair-toluene sulphonic acid in an organic solvent followed by reaction of the obtained complex with ester or amide derivatives of aliphatic or aromatic amino acids containing a primary or secondary amine group in the presence of a condensing agent and a base which are added successively.
EFFECT: method enables to obtain creatine amides using a much simpler technique and cheap raw material with higher output.
7 cl, 4 tbl, 10 ex
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