LEVODOPA MESYLATE PRODRUG, COMPOSITION THEREOF AND USE Russian patent published in 2011 - IPC C07C219/18 C07C229/36 A61K31/24 A61P25/16 A61P25/00 

Abstract RU 2429223 C2

FIELD: chemistry.

SUBSTANCE: invention relates to (2R)-2-phenylcarbonyloxypropyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate mesylate which is a levodopa prodrug and can be used to treat Parkinson's disease, schizophrenia, cognitive disorders, restless legs syndrome, periodic limp movement disorder, tardive dyskinesia, Huntington's disease, arterial hypertension and excessive diurnal drowsiness. The invention also relates to the crystalline form of the said compound, methods of producing said compound and its crystalline form, pharmaceutical compositions and treatment methods.

EFFECT: highly effective treatment.

46 cl, 6 dwg, 1 tbl, 7 ex

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RU 2 429 223 C2

Authors

Sjan Tszja-Nin

Daj Sjuehdun

Chzhou Sindi S.

Li Tszjan'Khua

Ngujen Mark K.

Dates

2011-09-20Published

2006-12-04Filed