STABLE FORMULATION OF AMORPHOUS PERIDONTOPRIL SALTS, METHOD FOR PREPARATION THEREOF, PARTICULARLY COMMERCIAL PRODUCTION THEREOF, AND APPLICATION THEREOF IN THERAPY OF HYPERTENSION Russian patent published in 2011 - IPC A61K38/55 A61K31/04 A61K9/16 A61K9/20 A61P9/12 

FIELD: medicine.

SUBSTANCE: invention refers to a stable trehalose-stabilised formulation of amorphous perindopril erbumine, a method for preparation thereof consisting in the fact that a perindopril erbumine hydrate is dissolved in water or a mixture of water and alcohol; an alkaline stabiliser solution and inert ingredients is added to this solution for producing a granulate, dried in vacuum or in air flow at 40°C and less to be granulated to produce granulate.

EFFECT: formulations have higher stability.

16 cl, 7 dwg, 1 tbl, 13 ex