METHOD FOR DIFFERENTIAL CORRECTION OF INFLAMMATION ACTIVITY IN BRONCHOPULMONARY DISEASES Russian patent published in 2011 - IPC A61N5/67 A61B5/00 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to pulmonology, and can be used in treating recurrent, chronic obstructive and nonobstructive bronchitis, acute complicated (severe) pneumonia, multiple bronchiectasis. A nasal and pharyngeal mucosa and a paravertebral reflexogenic zone at C₃ - C₄ and Th₂ - Th₅ levels are exposed to helium-neon laser emission (HNLE) of wave length 0.63 mcm in a constant mode, while projections of affected lung and bronchi zones and a pulmonary artery are exposed to infrared laser radiation (IRLR) of wave length 0.78-1.30 mcm in a pulse mode. It is preceded by determining a degree of inflammation activity (DIA) derived from a value of an integrative inflammation activity index (IAI). The IAI is calculated by formula: IAI = (IAI_clin+IAI_hem+IAI_cytol):3, where IAI_clin is a clinical IAI equal to X points of clinical inflammation activity markers of (CIM), n=8; IAI_hem is a hematological IAI equal to Σ points of hematological CIMs, n=9; IAI_cytol, is a cytological IAI equal to £ points of cytological CIMs, n=7. The absence of inflammation is diagnosed by the integrative IAI up to 0.1 points, the Ist DIA - by the IAI ranging within 0.1-1.1 point, the IInd DIA - by the IAI within 1.2-2.1 points, the IIIth DIA - by the IAI within 2.2 - 3.0. The the Ist DIA requires the HNLE exposure of the nasal, pharyngeal mucosa and the paravertebral reflexogenic zone at C₃ - C₄ and Th₂ - Th₅ level. Total power flow density (PFD) is 2.94-6.05 J/cm² for 4 min 55 sec - 9 min 05 sec in the course of 5-6 daily procedures. The IInd DIA requires the HNLE exposure of the nasal, pharyngeal mucosa and the paravertebral reflexogenic zone at C₃ - C₄ and Th₂ - Th₅ level and the IRLR exposure of a projection· of the affected lung and bronchi zones and the pulmonary artery with total PFD 3.04-6.46 J/cm² for 7 min 55 sec - 14 min 05 sec in the course of 7-8 daily procedures. The IIIrd DIA requires the IRLR exposure of the projections of the affected lung and bronchi zones and the pulmonary artery at total PFD 0.51-1.82 J/cm² for 16 min 00 sec - 22 min 30 sec in the course of 9-10 daily procedures.

EFFECT: method enables more effective correction of inflammation activity in bronchopulmonary diseases in children and adolescents with no cases of complications and side effects that indicates its safety, reduced length of inpatient treatment, prolonged remission, to decreased drug load.

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