METHOD OF PREDICTING DEVELOPMENT OF COMPLICATIONS OF HEMORRHAGIC FEVER WITH RENAL SYNDROME IN EARLY PERIOD OF DISEASE Russian patent published in 2011 - IPC G01N33/49 G01N33/53 

FIELD: medicine.

SUBSTANCE: invention describes method of estimating severity of course of hemorrhagic fever with renal syndrome, which includes determination of marker of vessel endothelium dysfunction in blood, where in blood plasma as marker of vessel endothelium dysfunction determined is concentration of antigen of inhibitor of plasminogen 1 type (IAP-1) activators in febrile period of disease and value of IAP-1 antigen concentration from 341.2 to 570.0 ng/ml is estimated as predictor of moderate form of disease, from 240.0 to 320.1 ng/ml - as predictor of severe form of disease without complications, from 138.3 to 75.5 ng/ml value is estimated as predictor of severe form of disease with complicated course.

EFFECT: invention makes it possible to estimate severity of HFRS course in order to predict in the earliest terms development of disease complications.

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