METHOD FOR PREDICTION OF SEVERITY OF HAEMORRHAGIC FEVER WITH RENAL SYNDROME Russian patent published in 2019 - IPC G01N33/49 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to a method for prediction of severity of haemorrhagic fever with renal syndrome. That is ensured by general and biochemical examination of blood, determining: hematocrit, relative content of segmented nuclear and salad leucocytes and monocytes, concentration of creatinine and C-reactive protein. Values of functions of classification of degrees of gravity HFRS are calculated by formulas: KF₁ = 21.881x₁ + 5.282x₂ + 0.579x₃ – 2.403x₄ + 2.273x₅ + 2.429x₆ – 859.400; KF₂ = 23.638x₁ + 3.502x₂ + 2.715x₃ – 0.572x₄ + 2.812x₅ + 2.344x₆ – 944.734; KF₃ = 32.120x₁ + 3.600x₂ + 2.490x₃ – 4.270x₄ + 4.640x₅ + 3.440x₆ – 1900.200, where KF₁ is the value of the FGR form light classification function; KF₂ – value of classification function of moderate form of HFRS; KF₃ is the value of the function of classification of the HFRS severe form; x₁ – hematocrit, %; x₂ – relative content of segment nuclear leukocytes, %; x₃ – relative odontocombular leukocyte content, %; x₄ is the relative monocyte content, %; x₅ – concentration of creatinine, mcMol/l; x₆ – concentration of C-reactive protein, mg/l, degree of severity of HFRS, which is taken to index classification function with highest value.

EFFECT: using the given method enables predicting the severity of hemorrhagic fever with renal syndrome, which enables optimizing the therapeutic approach of these patients.

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