DOSAGE FORMS CONTAINING TENELIGLIPTIN OXALATE SALTS AND SOLVATES THEREOF Russian patent published in 2021 - IPC A61K31/496 A61K9/20 A61K9/48 A61K47/00 A61P3/10 

FIELD: pharmaceuticals.

SUBSTANCE: group of inventions refers to a pharmaceutical composition for preventive or radical treatment of diabetes mellitus containing n.hydrate 2,5 teneligliptin oxalate or n.hydrate 3,0 teneligliptin oxalate, having a concentration in range of 0.5 wt % to 80 wt %, 10 wt% to 95 wt % of at least one pharmaceutically acceptable diluent, 0.1 wt % to 10 wt % binding substances, from 0.1 wt % to 20 wt % of lubricants, from 0.1 wt % to 30 wt % disintegrating agents and optionally from 0.05 wt % to 30 wt % stabilizing agents. Group of inventions also relates to a method of producing said pharmaceutical composition comprising steps of sieving, granulating, drying and screening the granulate, lubricating the sieved granulate and pressing the mixture to obtain a tablet or filling the mixture of capsules.

EFFECT: group of inventions provides stable pharmaceutical compositions of teneligliptin.

6 cl, 7 dwg, 26 tbl, 6 ex