FIELD: chemistry.
SUBSTANCE: invention relates to organic chemistry and specifically to a method of producing a Montelukast acid 
1 or sodium salt thereof through a reaction between a thiol compound of formula 
2 and an intermediate Montelukast compound of formula 
3 in the presence of a base in a media which contains a ionic liquid compound selected from a group of compounds of formulae 
4a-4e.
EFFECT: novel method of producing a Montelukast acid or sodium salt thereof, characterised by cost effectiveness and high output of the desired product.
8 cl, 1 tbl, 9 ex
| Title |
Year |
Author |
Number |
| METHOD OF PRODUCING MONTELUKAST AND INTERMEDIATE COMPOUND USED THEREIN |
2007 |
- Li Gvan Sun
- Chang Jang-Kil
- Li Dzaekheon
- Park Chul Khiun
- Park Eun-Dzu
- Joo Dzaekho
|
RU2408583C1 |
| METHOD OF PRODUCING MONTELUKAST AND COMPOUNDS FOR REALISING SAID METHOD |
2006 |
- Bartra Sanmarti Marti
- Gasans Gil'En Jolanda
- Koppi Laura
- Monsalvatkheh L'Jagostera Montserrat
- Talavera Ehskasani Pedro
|
RU2402532C2 |
| METHOD OF PRODUCING SODIUM SALT OF 1-[[[(R)-M-[(E)-2-(7-CHLORO-2-QUINOLYL)VINYL]-ALPHA-[O-(1-HYDROXY-1-METHYLETHYL)PHENETYL]BENZYL]THIO]METHYL]CYCLOPROPANE ACETIC ACID |
2008 |
- Zila Daniehl'
- Rinkievich Robert
- Krzhyzhanovski Mariush
- Ramza Jan
|
RU2436773C2 |
| METHOD OF PRODUCING (3S,4S)-4-((R)-2-(BENZYLOXY)TRIDECYL)-3-HEXYL-2-OXETANONE AND NOVEL INTERMEDIATE COMPOUND USED IN SAID METHOD |
2009 |
- Jun Sang Min
- Khong Dong Dzin
- Jang Veon Ki
- Joo Dzae Kho
- Kim Dzi Sook
- Li Moon Sub
- Kim Khan Kiong
- Lim Eun Dzung
- Moon Joung Kho
- Chang Joung-Kil
- Li Gvan Sun
|
RU2471790C1 |
| HETEROARYL PIPERAZINE DERIVATIVE, METHOD FOR ITS PREPARATION AND APPLICATION IN MEDICINE |
2018 |
- Li, Sin
- Khe, Vej
- Chen, Yan
- Khe, Fen
- Tao, Vejkan
|
RU2745431C1 |
| PYRONE DERIVATIVES AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, INTERMEDIATE COMPOUNDS FOR PREPARATION THEREOF, PHARMACEUTICAL COMPOSITION HAVING ANTIVIRAL AND ANTIBACTERIAL ACTIVITY BASED THEREON, AND METHOD OF TREATING RETROVIRUS- INDUCED INFECTIONS AND DISEASES |
1994 |
- Ehdmund Li Ehllsvort
- Ehlizabet Lannej
- Bradlej Din Tejt
|
RU2160733C2 |
| NEW METHOD FOR PREPARING 5-(4-FLUOROPHENYL)-1-[2-(2R,4R)-4-HYDROXY-6-OXOTETRAHYDROPYRAN-2-YL)ETHYL]-2-ISOPROPYL-4-PHENYL-1H-PYRROL-3-CARBOXYLI9C ACID PHENYLAMIDE |
2001 |
- Batler Donal'D Judzhin
- Dedzhong Rehndoll Li
- Nel'Son Dzhejd Duglas
- Pammen Majkl Zherar
- Stak Timoti Li
|
RU2244714C1 |
| PYRIMIDINE DERIVATIVE THAT SUPPRESSES CANCER CELL GROWTH AND MEDICAL APPLICATION THEREOF |
2020 |
- Ryu, Hyung-Chul
- Kim, Jae-Sun
- Kim, Sung-Eun
- Lee, Sun-Ho
- Lee, Yong-Hyub
|
RU2792849C1 |
| NEW OXAZOLIDINONE DERIVATIVE AND PHARMACEUTICAL COMPOSITION THAT INCLUDES IT |
2012 |
- Cho Joung Lag
- Baek Sung Joon
- Chae Sang Eun
- Kim Sun Yang
- Li Khong Bum
- Li Khiang Sook
- Okh Kiuman
- Kheo Khie Dzin
- Park Tae Kio
- Voo Sung Kho
- Kim Jong Zu
|
RU2617408C2 |
| DERIVATIVES OF 5,6-DIHYDROPYRONE AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF |
1994 |
- Ehdmund Li Ehl'Svors
- Ehlizabet Lanni
- Bredli Din Tajt
|
RU2140917C1 |
