2-METHOXY-4[(3aR,7aS)-3,3,6-TRIMETHYL-1,3,3a,4,5,7a-HEXAHYDRO-2-BENZOFURAN-1-YL]PHENOL - NOVEL AGENT FOR TREATING PARKINSON'S DISEASE Russian patent published in 2011 - IPC C07D307/87 A61K31/343 A61P25/16 

Abstract RU 2436782 C1

FIELD: chemistry.

SUBSTANCE: invention relates to pharmaceutical chemistry and specifically 2-methoxy-4-[(3aR,7aS8)-3,3,6-trimethyl-1,3,3a,4,5,7a-hexahydro-2-benzofuran-1-yl]phenol of formula 1, , having anti-Parkinson activity and can be used in medicine.

EFFECT: agent has low toxicity and can be obtained from common natural compounds 2- and 3-carenes.

5 ex, 2 tbl

Similar patents RU2436782C1

Title Year Author Number
MEDICATION FOR TREATING PARKINSON'S DISEASE 2009
  • Tolstikova Tat'Jana Genrikhovna
  • Pavlova Alla Viktorovna
  • Morozova Ekaterina Aleksandrovna
  • Il'Ina Irina Viktorovna
  • Ardashov Oleg Vasil'Evich
  • Volcho Konstantin Petrovich
  • Salakhutdinov Nariman Faridovich
RU2418577C1
2-((1-(4R-BENZYL)-1H-1,2,3-TRIAZOL-4-YL)METHOXY)-3-METHYL-6-(PROP-1-en-2-YL)CYCLOHEX-3-en-1-ol AS ANTIPARKINSONIAN AGENT 2023
  • Podturkina Aleksandra Vladimirovna
  • Ardashov Oleg Vasilevich
  • Pavlova Alla Viktorovna
  • Tolstikova Tatyana Genrikhovna
  • Volcho Konstantin Petrovich
  • Salakhutdinov Nariman Faridovich
RU2812081C1
2-((1H-1,2,4-TRIAZO-3-YL)THIO)-3-METHYL-6-(PROP-1-EN-2-YL)CYCLOHEX-3-EN-1-OL AS AN ANTIPARKINSONIAN AGENT 2022
  • Podturkina Aleksandra Vladimirovna
  • Kotliarova Anastasiia Anatolevna
  • Pavlova Alla Viktorovna
  • Sidorova Iuliia
  • Tolstikova Tatiana Genrikhovna
  • Volcho Konstantin Petrovich
  • Salakhutdinov Nariman Faridovich
RU2796729C1
3-METHYL-6-(PROP-1-EN-2-YL)CYCLOHEX-3-EN-1,2-DIOL- EPOXIDES - NEW ANTIPARKINSONIAN DRUGS AND ANTI-CONVULSANTS 2014
  • Ardashov Oleg Vasil'Evich
  • Pavlova Alla Viktorovna
  • Korchagina Dina Vladimirovna
  • Tolstikova Tat'Jana Genrikhovna
  • Volcho Konstantin Petrovich
  • Salakhutdinov Nariman Faridovich
RU2571299C1
AGENT FOR TREATMENT AND PREVENTION OF PARKINSON'S DISEASE 2006
  • Kovalev Georgij Ivanovich
  • Abaimov Denis Aleksandrovich
  • Firstova Julija Jur'Evna
  • Balakshin Vladimir Vladimirovich
  • Chistjakov Aleksej Nikolaevich
RU2324492C1
INJECTABLE DOSAGE FORM FOR TREATMENT OF PARKINSON'S DISEASE, METHOD FOR PREPARING AND USING IT 2011
  • Seredenin Sergej Borisovich
  • Voronina Tat'Jana Aleksandrovna
  • Pjatin Boris Mikhajlovich
  • Kapitsa Inga Gennadievna
  • Val'Dman Elena Arturovna
  • Nerobkova Ljubov' Nikolaevna
  • Avdjunina Nina Ivanovna
  • Alekseev Konstantin Viktorovich
  • Grushevskaja Ljubov' Nikolaevna
  • Blynskaja Evgenija Viktorovna
  • Sergeeva Marija Sergeevna
RU2520758C2
NOVEL USING SUBSTITUTED AMINOMETHYLCHROMANS IN TREATMENT OF MOTION DISORDER OR UNDESIRABLE EFFECT CAUSED BY AGENTS THAT ARE ADMINISTRATED IN TREATMENT OF EXTRAPYRAMID MOTION DISORDER 2002
  • Bartoshik Gerd
  • Russ Germann
  • Zejfrid Kristof
  • Bettkher Khenning
  • Bokel' Khajnts-Germann
  • Shmid-Grossmann Ushi
RU2320336C2
ADAMANTYL DERIVATIVES OF BENZIMIDAZOLE, HAVING ANTIPARKINSONIAN ACTIVITY 2023
  • Kapitsa Inga Gennadievna
  • Voronina Tatyana Aleksandrovna
  • Kravtsova Oksana Yurevna
  • Zherdev Vladimir Pavlovich
  • Zajtseva Nadezhda Mikhajlovna
  • Ustinova Mariya Isaakovna
  • Grushevskaya Lyubov Nikolaevna
  • Seredenin Sergej Borisovich
  • Vakhitova Yuliya Venerovna
RU2820315C1
METHOD OF CORRECTING TREMOR IN EXPERIMENT 2018
  • Korokin Mikhail Viktorovich
  • Pokrovskij Mikhail Vladimirovich
  • Avdeeva Natalya Viktorovna
  • Pobeda Anna Sergeevna
RU2678977C1
BIOLOGICALLY ACTIVE HETEROGLYCOSIDE FOR CORRECTION OF PATHOLOGICAL STATES OF CENTRAL NERVOUS SYSTEM 2006
  • Stovbun Sergej Vital'Evich
  • Litvin Aleksandr Anatol'Evich
  • Jakimuk Pavel Vasil'Evich
  • Sergienko Valerij Ivanovich
RU2335289C2

RU 2 436 782 C1

Authors

Tolstikova Tat'Jana Genrikhovna

Pavlova Alla Viktorovna

Morozova Ekaterina Aleksandrovna

Il'Ina Irina Viktorovna

Volcho Konstantin Petrovich

Salakhutdinov Nariman Faridovich

Dates

2011-12-20Published

2010-06-10Filed