FIELD: chemistry.
SUBSTANCE: described is a novel method for convergent synthesis of calicheamicin derivatives of formula 
(where W denotes calicheamicin, and values of the rest of the radicals are disclosed in the claim) using intermediate compounds which are bifunctional linkers of formula 
and trifunctional linkers of formula 
.
EFFECT: high output of desired compounds, shorter duration of synthesis, low risk of workers being affected by aggressive calicheamicin derivatives.
24 cl, 8 ex
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