METHOD OF TREATING BENIGN HYPERPLASTIC ENDOMETRIAL PROCESSES IN PATIENTS WITH METABOLIC SYNDROME Russian patent published in 2012 - IPC A61K31/175 A61K31/575 A61P3/00 A61H1/00 A23L1/29 G01N33/48 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to gynaecology, and can be used for treating hyperplastic endometrial processes in patients with metabolic syndrome. A method involves enzyme immunoassay of blood serum to determine a progesterone level, and if its concentration is 8.0 nmol/l and higher, metabolic therapy including administration of methphormin 1000 mg × 2 times a day, hypo-calorie diet with calorage limited to 1500 kcal a day and increased physical activity in the form of intensive walking. The progesterone concentration lower than 8.0 nmol/l requires additionally another enzyme immunoassay of blood serum to evaluate a leptin level, and if its value is lower than 57.18 ng/ml, the metabolic therapy described above is prescribed. If the leptin level exceeds 57.18 ng/ml, the patients require a combined metabolic and hormonal therapy consisting in administration of methphormin 1000 mg × 2 times a day, dufaston 10 mg × 2 times a day starting with the 16th for 25th day of a menstrual cycle, hypo-calorie diet with calorage limited to 1500 kcal a day and graduated physical activity in the form of walking starting with 10 minutes to be gradually increased to 40 minutes in day.

EFFECT: method allows preserving the reproductive function.

1 dwg, 3 ex