WATER-SOLUBLE COMPOSITION, POSSESSIVE PROPERTIES OF CARDIO-PROTECTOR Russian patent published in 2012 - IPC A61K38/28 A61K33/14 A61K31/7004 A61K31/194 A61K31/295 A61P9/00 

Abstract RU 2438698 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to field of medicine and chemical-pharmaceutical industry, in particular, to medication, applied in case of myocardial infarction and operations on heart in conditions of artificial blood circulation. Water-soluble composition for intravenous introduction, contains ingredients with the following component ratio in wt %: D-glucose 23.40-28.60; potassium chloride 0.14-0.16; potassium salt of L-asparaginic acid 0.81-0.99; semi-magnesium salt of L-asparagenic acid (magnesium L-aspartate) 0.72-0.88; human insulin genetically engineered (in IU/l) 54.00-66.00; dinitrosyl complex of iron (II) with glutathione 0.19-0.23; water for injections - remaining part, with solution pH 7.4±0.1 at 22°C.

EFFECT: application of composition ensures limitation of myocardial infraction size, recovery of metabolic condition of heart at reperfusion, reduces injury of membranes of post-ischemic cardiomyocytes with smaller haemodinamics disorders as compared with traditionally applied medications.

2 dwg, 7 tbl, 4 ex

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RU 2 438 698 C1

Authors

Pisarenko Oleg Ivanovich

Serebrjakova Larisa Ivanovna

Studneva Irina Mikhajlovna

Tskitishvili Ol'Ga Vladimirovna

Vanin Anatolij Fedorovich

Dates

2012-01-10Published

2010-05-12Filed