FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to phthisiology and pharmaceutical industry. A method for preparing a water-soluble chitosan para-aminosalicylate consists in preparing an aqueous solution of para-aminosalicylic acid (2.8 wt %) at temperature 90°C, adding low-molecular chitosan (low molecular weight 3.9 and 30 kDa) in amount 2.8 wt % in mixing with a mechanical mixer, dispersing a reaction mixture at temperature 85°C for 40 minutes. After termination of the process, the reaction mixture is vacuumised; a solid residue is dried in vacuum at temperature 30°C.
EFFECT: preparation of medicines for tuberculosis.
3 ex, 9 dwg
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Authors
Dates
2012-01-20—Published
2010-11-25—Filed