METHOD FOR PREPARING WATER-SOLUBLE CHITOSAN PARA-AMINOSALICYLATE Russian patent published in 2012 - IPC A61K31/195 A61K31/722 A61K47/48 A61P31/06 

Abstract RU 2440111 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to phthisiology and pharmaceutical industry. A method for preparing a water-soluble chitosan para-aminosalicylate consists in preparing an aqueous solution of para-aminosalicylic acid (2.8 wt %) at temperature 90°C, adding low-molecular chitosan (low molecular weight 3.9 and 30 kDa) in amount 2.8 wt % in mixing with a mechanical mixer, dispersing a reaction mixture at temperature 85°C for 40 minutes. After termination of the process, the reaction mixture is vacuumised; a solid residue is dried in vacuum at temperature 30°C.

EFFECT: preparation of medicines for tuberculosis.

3 ex, 9 dwg

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RU 2 440 111 C1

Authors

Kupreev Nikolaj Iosifovich

Kuznetsov Vjacheslav Alekseevich

Bolgov Aleksej Aleksandrovich

Dates

2012-01-20Published

2010-11-25Filed