FIELD: medicine, pharmaceutics.
SUBSTANCE: present invention refers to compounds of formula (I) or formula (I') where values of the substitutes are disclosed in the patent claim. The present compounds are able to inhibit Rho-kinase.
EFFECT: making the compounds effective for treating and/or preventing the Rho-kinase-associated and/or Rho-kinase-mediated diseases by phosphorylation of myosin light chain phosphatise.
Title | Year | Author | Number |
---|---|---|---|
CYCLOALKYLAMINE-SUBSTITUTED ISOQUINOLONE DERIVATIVES | 2007 |
|
RU2457203C2 |
CYCLOALKYLAMINE-SUBSTITUTED ISOQUINOLINE AND ISOQUINOLINONE DERIVATIVES | 2007 |
|
RU2468011C2 |
ISOQUINOLINE DERIVATIVES AS Rho-KINASE INHIBITORS | 2006 |
|
RU2443688C2 |
PIPERADINYL-SUBSTITUTED ISOQUINOLONE DERIVATIVES AS Rho-KINASE INHIBITORS | 2006 |
|
RU2414467C2 |
SUBSTITUTED ISOQUINOLINE AND ISOQUINOLINONE DERIVATIVES AS Rho-KINASE INHIBITORS | 2007 |
|
RU2455302C2 |
6-SUBSTITUTED ISOQUINOLINES AND ISOQUINOLINONES EFFECTIVE AS Rho-KINASE INHIBITORS | 2009 |
|
RU2528229C2 |
BI- AND POLYCYCLIC SUBSTITUTED ISOQUINOLINE AND ISOQUINOLINONE DERIVATIVES, USEFUL AS RHO-KINASE INHIBITORS | 2009 |
|
RU2532481C2 |
SUBSTITUTED ISOQUINOLINES AND ISOQUINOLINONES AS Rho-KINASE INHIBITORS | 2009 |
|
RU2538588C2 |
PYRAZOLOPYRIDINE DERIVATIVES AS KINASE 1β-ADRENERGIC RECEPTOR INHIBITORS | 2006 |
|
RU2415855C2 |
ANTIVIRAL COMPOUNDS | 2009 |
|
RU2505540C2 |
Authors
Dates
2012-01-27—Published
2006-07-20—Filed