CYCLOHEXYLAMINIZOQUINOLONE AS Rho-KINASE INHIBITORS Russian patent published in 2012 - IPC C07D217/24 A61K31/472 A61P9/12 

Abstract RU 2440988 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to compounds of formula (I) or formula (I') where values of the substitutes are disclosed in the patent claim. The present compounds are able to inhibit Rho-kinase.

EFFECT: making the compounds effective for treating and/or preventing the Rho-kinase-associated and/or Rho-kinase-mediated diseases by phosphorylation of myosin light chain phosphatise.

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RU 2 440 988 C2

Authors

Plettenburg Oliver

Khofmajster Armin

Kaderajt Diter

Brendel' Joakhim

Len Mattias

Dates

2012-01-27Published

2006-07-20Filed