FIELD: chemistry.
SUBSTANCE: compounds are suitable for use as kinase 1β-adrenergic receptor (βARK-1) inhibitors. The invention also relates to compositions containing such compounds and to use of compounds of formula to treat and prevent chronic heart failure, hypertension myocardial ischemia and hepatitis C viral infections (HCV) and for preventing opiate addiction. The invention also pertains to methods of producing formula (I) compounds.
EFFECT: more effective use of the compounds.
11 cl, 2 tbl
Title | Year | Author | Number |
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ISOQUINOLINE DERIVATIVES AS Rho-KINASE INHIBITORS | 2006 |
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RU2443688C2 |
PIPERADINYL-SUBSTITUTED ISOQUINOLONE DERIVATIVES AS Rho-KINASE INHIBITORS | 2006 |
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RU2414467C2 |
CYCLOALKYLAMINE-SUBSTITUTED ISOQUINOLONE DERIVATIVES | 2007 |
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RU2457203C2 |
SUBSTITUTED ISOQUINOLINE AND ISOQUINOLINONE DERIVATIVES AS Rho-KINASE INHIBITORS | 2007 |
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RU2455302C2 |
NEW FIVE-MEMBER HETEROCYCLES, THEIR PREPARING, THEIR APPLYING AND PHARMACEUTICAL PREPARATIONS COMPRISING THEREOF | 1998 |
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RU2240326C2 |
CYCLOHEXYLAMINIZOQUINOLONE AS Rho-KINASE INHIBITORS | 2006 |
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RU2440988C2 |
STIMULATING AGENTS OF GROWTH HORMONE SECRETION | 1996 |
|
RU2172742C2 |
ISOXAZOLINES AND ISOXAZOLES, METHOD OF INHIBITION OF PLATELET AGGREGATION, PHARMACEUTICAL COMPOSITION INHIBITING PLATELET AGGREGATION | 1994 |
|
RU2149871C1 |
AZOLOPYRIDIN-2-ONE DERIVATIVES AS LIPASE AND PHOSPHOLIPASE INHIBITORS | 2006 |
|
RU2414473C2 |
SUBSTITUTED DERIVATIVES OF IMIDAZOLIDINE, METHOD FOR PREPARING AND PHARMACEUTICAL PREPARATION | 1998 |
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RU2239641C2 |
Authors
Dates
2011-04-10—Published
2006-06-13—Filed