IMPROVED WAY OF PREPARATION OF THE ACTIVE COMPONENT FIRM DISPERSION Russian patent published in 2012 - IPC A61K9/10 A61K9/20 B29C47/00 B29C47/10 B29C47/44 B29C47/46 B29C47/64 B29C47/88 B29C31/00 

FIELD: technology.

SUBSTANCE: invention concerns the way of preparation of the active component firm dispersion which includes loading of the active component and matrixforming agent in extrusion machine and preparation of homogeneous extrudate. Extrudate includes, at least, two rotating shaft (2), where each of shaft (2) bears set of the processing elements located axially one after another, which form a loading and moving zone (A), at least, one zone with a return carving (R;D) and an unloading zone (E). The processing elements forming a zone with a return carving (R;D), contain, at least, two elements with a return carving (14), each of which is based on the worm element having a direction of moving, opposite to the general direction of movement extrudate. Thus one worm element with a carving clockwise (3) is located between the specified two elements with a return carving (14) where the step of a carving of an element with a return carving (14) makes from (-0,8) to (-1,2) time from a step of a carving of a worm element with a carving clockwise (3).

EFFECT: invention provides high degree of mixing and homogenization at smaller destruction of an active component, and also the best effect of self-cleaning.

25 cl, 10 dwg, 7 tbl, 3 ex