FIELD: medicine, pharmaceutics.
SUBSTANCE: pharmaceutical dosed form contains a hard dispersion product of, at least, one active ingredient, dispersed in a polymer carrier composition. The polymer carrier composition contains a) vinylpyrrolidone homopolymer, in which, at least, 95 wt % of homopolymer have a molecular weight in the range from 1000 to 13000; and b) vinylpyrrolidone copolymer, which has an average molecular weight from 5000 to 1500000. The dosed form, preferably, is obtained by a melt extrusion method.
EFFECT: polymer carrier composition by the invention forms from the said polymers a homogeneous mixture which has only one vitrification temperature Tg, and has high ability to dissolve a medication.
13 cl, 5 dwg, 1 ex
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Authors
Dates
2014-06-20—Published
2009-06-30—Filed