AGENT HAVING ANTIBACTERIAL ACTIVITY Russian patent published in 2012 - IPC C07D487/08 A61K31/4995 A61P31/04 A61P31/12 

Abstract RU 2443705 C1

FIELD: chemistry.

SUBSTANCE: disclosed is an agent which is 1,5-bis-(4-dodecyl-1,4-diazoniabicyclo[2.2.2]octan-1-yl)pentane dichloride dibromide with a structural formula shown on dwg. 1, which can be used to treat viral diseases of animals (e.g., bovine virus diarrhoea), accompanied by bacterial infections. Synthesis of the disclosed compound takes place in methanol as a solvent in 20-24 hours with molar ratio of the following components: 1-dodecyl-4-aza-1-azoniabicyclo[2.2.2]octane chloride to 1,5-dibromopentane equal to 1:(2.0-2.16), with 80.4-83.7% output of the end product.

EFFECT: agent has low toxicity, is stable during storage at room temperature for 3 years, has marked antibacterial action on pathogenic strains of microorganisms.

1 cl, 2 dwg, 3 tbl, 6 ex

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RU 2 443 705 C1

Authors

Sil'Nikov Vladimir Nikolaevich

Burakova Ekaterina Anatol'Evna

Glotova Tat'Jana Ivanovna

Glotov Aleksandr Gavrilovich

Repin Vladimir Evgen'Evich

Dates

2012-02-27Published

2010-11-26Filed