PHARMACEUTICAL FORMULATION IN SOLID DOSAGE FORM AND METHOD FOR PREPARING IT Russian patent published in 2012 - IPC A61K31/4412 A61K31/40 A61P25/28 A61P9/10 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to chemical-pharmaceutical industry, and concerns a pharmaceutical composition possessing antihypoxic properties, improving coronary and cerebral circulation, improving cognitive functions, having antioxidant, antiischemic and hypolipidemic action, containing as active substances a therapeutically effective amount of 2-ethyl-6-methyl-3-oxypyridine succinate and atorvastatin, as well as pharmaceutically acceptable target additives applicable in solid dosage forms containing: a group of excipients and strength enhancing agents: lactose, dibasic calcium phosphate or microcrystalline cellulose, a group of binding substances: starch, polyvinylpyrrolidone or oxypropylmethylcellulose, a group of substances providing adequate flowability and preventing adhesion - aerosil, calcium stearate, magnesium stearate. The composition is presented in the solid dosage form such as a powder, a granule, a capsule or a tablet.

EFFECT: composition shows high bioavailability.

6 cl, 7 ex, 7 tbl