BICYCLIC GAMMA AMINO ACID DERIVATIVE Russian patent published in 2012 - IPC C07C229/28 C07C323/58 A61K31/195 A61K31/215 A61P25/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to a compound of general formula (I), in the form of optical isomers or their mixtures, and its pharmaceutically acceptable salt, which show activity as α₂δ ligand and affinity to a subunit of α₂δ potential-dependent calcium channels. In formula each R¹, R², R²', R⁴, R⁵, R⁸ and R⁸' independently represents hydrogen atom, halogen atom or C1-C6 alkyl group; each R⁶ and R⁷ independently represents hydrogen atom or C1-C6 alkyl group; or R² and R^2' together with carbon atom whereto attached form C3-C7 cycloalkyl group; R³ represents hydrogen atom, C1-C6 alkyl group, C1-C6 alkylhalogenide group, C1-C6 alkoxy-C1-C6 alkyl group, C2-C6 alkenyl group, C2-C6 alkynyl group, C1-C6 alkylsulphanyl-C1-C6 alkyl group, C2-C7 acyloxy-C1-C6 alkyl group or C3-C7 cycloalkyl group.

EFFECT: preparing the pharmaceutical composition for treating and/or preventing pain.

25 cl, 19 tbl, 43 ex