METHOD FOR SURGICAL MANAGEMENT OF ACUTE THROMBOEMBOLIA OF PULMONARY ARTERY Russian patent published in 2012 - IPC A61M1/10 A61K31/573 A61K31/47 A61K33/14 A61K35/14 A61P43/00 A61B17/00 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, specifically cardiosurgery, and may be used for treating thromboembolia of pulmonary artery. For this purpose a surgical intervention accompanied by artificial circulation involves mechanical thrombus removal from greater branches of the pulmonary artery. It is followed by exposing a left atrium and conducting a retrograde pulmonary perfusion by sequential perfusion of each of the four pulmonary veins for 4 minutes by a combination solution. The combination solution is prepared by mixing blood from a pump oxygenator and a protective solution in proportions 3:1. The protective solution consists of 0.9% sodium chloride 800 ml, dexamethasone 16 ml, actovegin 400 ml and 15% mannitol 100 ml. The perfusion procedure is conducted at volumetric speed 200-250 ml/min and perfusion pressure 20 mm Hg. Thromboemboles are removed from peripheral parts of the pulmonary artery by aspiration of blood stream from the incised pulmonary artery. The procedure is terminated with hermetically closed wound of the pulmonary artery. A left atrium cavity is closed with recovering cardiac activity, and the incisional wound is closed in layers.

EFFECT: method provides considerably reduced death rate and risk of postoperative complications in the case patients, as well as provided effective removal of small thromboembols from the peripheral parts of the pulmonary artery and prevented developing air embolism of the pulmonary artery.

1 tbl, 1 ex