FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to an amorphous form of N-{2- fluorine-5-[3-(thiophen-2-carbonyl)-pyrazolo[1,5-a]-pyrimidin-7-yl]-phenyl}-N-methyl-acetamide, methods for preparing it.
EFFECT: preparing the pharmaceutical compositions for GABA-receptor inhibition containing said form, and also to using them as a drug for treating and/or preventing anxiety, epilepsy, sleeping disorder and sleeplessness, for induction of sedative-hypnotic effect, for anaesthesia and muscular relaxation and for time modulation required for sleep induction and duration.
12 cl, 4 dwg
| Title |
Year |
Author |
Number |
| POLYMORPHIC MODIFICATION IN N-{5-[3-(THIOPHENE-2-CARBONYL)-PYRAZOLO[1,5-a]PYRIMIDIN-7-YL]-2-FLUORO-PHENYL}-N-METHYL-ACETAMIDE (VERSIONS), CONTAINING IT PHARMACEUTICAL COMPOSITION (VERSIONS), MEDICATION, METHOD OF OBTAINING SAID POLYMORPHIC MODIFICATION (VERSIONS) AND METHOD OF TREATMENT AND/OR PREVENTION OF NERVOUS DISORDERS |
2007 |
- Anglada Luis
- Gul'Etta Antonio
- Palomer Al'Bert
|
RU2413729C2 |
| METHOD OF PRODUCING N-{5-[3-(THIOPHENE-2-CARBONYL)-PYRAZOLE[1,5-a]PYRIMIDIN-7-YL]-2-FLUORO-PHENYL}-N-METHYL-ACETAMIDE IN POLYMORPHIC MODIFICATION B |
2007 |
- Anglada Luis
- Gul'Etta Antonio
- Palomer Al'Bert
|
RU2404984C1 |
| PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION SHOWING ABILITY TO INHIBIT GABA RECEPTORS, AND DRUG FOR TREATING AND PREVENTING DISORDERS ASSOCIATED WITH GABA RECEPTOR INHIBITION |
2007 |
- Anglada Luis
- Gul'Etta Antonio
- Palomer Al'Bert
|
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| HALOGENISED PYRAZOLO[1,5-a]PYRIMIDINES (VERSIONS), METHODS FOR PREPARING THEM, BASED PHARMACEUTICAL COMPOSITION, INTERMEDIATE COMPOUNDS AND METHOD FOR PREPARING THEM (VERSIONS) |
2006 |
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- Gul'Etta Antonio
- Palomer Al'Bert
|
RU2478101C2 |
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|
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|
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2007 |
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