CHLOROPROPOXY DERIVATIVES OF 7-OXO-COUMARIN, HAVING TRANQUILISING AND HEPATOPROTECTIVE ACTION Russian patent published in 2012 - IPC C07D311/16 A61K31/352 A61P25/00 

Abstract RU 2452732 C2

FIELD: chemistry.

SUBSTANCE: invention relates to novel chloropropoxy derivatives of 7-oxo-coumarin of general formula: , where a) 7-(3'-chloropropoxy)-3,4-trimethylene-5,6-benzo-α-pyrone, where: R=H; R1 and R2=-CH2-CH2-CH2- b) 7-(2'-methyl-3'-chloropropoxy)-5,6-benzo-α-pyrone, where: R=CH3; R1=R2=H, which have tranquilising and hepatoprotective action, as well as use thereof as tranquilising and hepatoprotective agents.

EFFECT: low toxicity with high biological activity.

2 cl, 10 tbl

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RU 2 452 732 C2

Authors

Denisenko Petr Prokof'Evich

Tarasenko Aleksandr Aleksandrovich

Dates

2012-06-10Published

2010-03-31Filed