FIELD: medicine, pharmaceutics.
SUBSTANCE: present invention refers to immunology. What is presented is using immunotherapy for the purpose of inducing atherosclerotic plaque regression, involving introducing oxidised low-density lipoproteins (LDLP) containing the epitope ApoB-100, or antibodies thereto. There are also contemplated a method of inducing atherosclerotic plaque regression, a method of treating, using oxidised oxidised LDLP epitopes and antibodies thereto for preparing a drug, a pharmaceutical composition, a set, and also methods of identifying antibodies and agents which induce atherosclerotic plaque regression.
EFFECT: use of the present invention can find further application in treating various atherosclerosis-related diseases.
73 cl, 7 dwg, 2 tbl, 4 ex
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