METHOD OF DIFFERENTIAL PRESCRIPTION OF β-ADRENORECEPTOR BLOCKING AGENTS IN PATIENTS WITH CHRONIC CARDIAC FAILURE Russian patent published in 2012 - IPC A61K31/138 A61P9/04 G01N33/48 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely cardiology, and may be used for differential prescription of β-adrenoreceptor blocking agents in patients with chronic cardiac failure (CCF). That is ensured by determining the β₁-adrenoreceptor gene polymorphism, and the β-adrenoreceptor blocking agent is prescribed only in the patients with Arg/Arg genotype of the β₁-adrenoreceptor gene The βadrenoreceptor blocking agents 12.5-50 mg/day is introduced daily in the morning and in the evening in the equal amount for 24 weeks.

EFFECT: method allows selecting the appropriate therapy in the CCF patients.

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