METHOD FOR STIMULATING LIVER REGENERATION IN FIBROTIC CHANGES IN EXPERIMENT Russian patent published in 2012 - IPC G09B23/28 A61M37/00 A61K35/48 A61P1/16 A61P41/00 

Abstract RU 2455701 C1

FIELD: medicine.

SUBSTANCE: under the conditions of modelling cirrhosis in experiment, the preparation EMBRYOBLASTE is introduced in liver tissue by means of an injector needle at the depth up to 0.1 cm. The preparation is introduced along a front surface of the liver, 2 injections in each lobe of the liver to form a papula. The volume of one injection makes 0.3 ml.

EFFECT: reduced fibrotic regeneration of liver tissue by means of intensifying liver cell proliferation and extracellular matrix resorption with reducing a degree of manifestation of venular and periportal fibrosis, reducing haemo- and lymphostasis, regenerating capillarisation of liver sinusoids without affecting cell architectonics of the organs.

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Authors

Dudarev Vadim Aleksandrovich

Kirgizov Igor' Vital'Evich

Jakimova Svetlana Ivanovna

Fokin Dmitrij Vladimirovich

Vorob'Eva Evgenija Leonidovna

Skladneva Valerija Olegovna

Dates

2012-07-10Published

2011-02-28Filed