FIELD: medicine, pharmaceutics.
SUBSTANCE: group of inventions refers to application of an antisecretory factor, such as an antisecretory protein (AF), its homologue, and/or a fragment possessing antisecretory activity wherein the specified protein (AG) is related with an amino acid sequence presented in SEQ ID NO:6 and/or wherein the specified fragment contains the amino acid sequence presented in SEQ ID NO:4 for preparing a pharmaceutical composition applicable in treatment or prevention of intraocular pressure increase. Also, the invention concerns a peptide presented in SEQ ID NO:4, possessing antisecretory activity for prevention or treatment of intraocular pressure increase.
EFFECT: group of inventions provides the new therapeutic approach to treatment and/or prevention of such condition reducing the intraocular pressure to an acceptable level, optionally 21 mm Hg or less.
20 cl, 17 ex
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