ANTIBODIES RECOGNISING CARBOHYDRATE CONTAINING EPITOPE ON CD-43 AND CEA EXPRESSED ON CANCER CELLS, AND METHODS OF USING SUCH Russian patent published in 2012 - IPC C07K16/28 C07K16/30 A61K39/395 A61P35/00 C12N15/63 C07K19/00 

FIELD: medicine.

SUBSTANCE: invention represents versions of antibodies specifically binding to an extracellular domain of human CD43 or human CEA expressed by nonhematopoietic cancer cells. Said antibodies are characterised by amino acid sequences of either three heavy and light chain CDR, or amino acid sequences VH and VL. There are also presented an antibody conjugate with a cytotoxic agent; a host cell producing the antibody; a composition for nonhematopoietic cancer; a polynucleotide; an antibody expression vector.

EFFECT: versions of a method of treating nonhematopoietic cancer.

29 cl, 16 dwg, 6 tbl, 10 ex