COVALENT DIABODIES AND USE THEREOF Russian patent published in 2021 - IPC A61K39/00 

Abstract RU 2744176 C2

FIELD: biotechnology; medicine.

SUBSTANCE: invention relates to molecules of diabodies and to their use for treating various diseases and disorders, including immunological disorders, infectious disease, intoxication and malignant tumors. According to the invention, the diabodies molecules contain two polypeptide chains which are associated with the formation of at least two epitope binding sites, which can recognize one or different epitopes on one or different antigens.

EFFECT: invention can be used for effective treatment of autoimmune disorder.

29 cl, 49 dwg, 17 tbl, 1 ex

Similar patents RU2744176C2

Title Year Author Number
TUMOR-TARGETED AGONISTIC CD28-ANTIGEN-BINDING MOLECULES 2019
  • George Guy
  • Hofer Thomas
  • Hosse Ralf
  • Klein Christian
  • Moessner Ekkehard
  • Sam Johannes
  • Umana Pablo
  • Thom Jenny Tosca
  • Gasser Stephan
  • Vallier Jean-Baptiste Pierre
  • Fauti Tanja
RU2808030C2
BISPECIFIC ANTIGEN-BINDING MOLECULES CONTAINING ANTI-FAP CLONE 212 2019
  • Bruenker Peter
  • Duerr Harald
  • Klein Christian
  • Umana Pablo
  • Bujotzek Alexander
  • Zielonka Joerg
  • Trumpfheller Christine
  • Rapp Moritz
  • Le Clech Marine
RU2799429C2
BISPECIFIC 2+1 ANTIBODIES 2018
  • Amann Maria
  • Ferrara Koller Claudia
  • Flury Reto
  • Georges Guy
  • Grau-Richards Sandra
  • Haas Alexander
  • Hesse Friederike
  • Imhof-Jung Sabine
  • Klein Christian
RU2797305C2
IL2 AND MUTANT TNF IMMUNOCONJUGATES 2017
  • Neri, Dario
  • De Luca, Roberto
  • Wulhfard, Sarah
RU2758139C2
TRISPECIFIC BINDING MOLECULES FOR TREATING VIRAL HEPATITIS B INFECTION AND BOUND STATES 2016
  • Protzer, Ulrike
  • Bohne, Felix
  • Quitt, Oliver
  • Momburg, Frank
  • Moldenhauer, Gerhard
RU2733496C2
BISPECIFIC ANTIBODIES SPECIFIC RELATIVELY TO COSTIMULATORY TNF-RECEPTOR 2016
  • Amann Mariya
  • Bryunker Peter
  • Klaus Kristina
  • Ferrara Koller Klaudiya
  • Grau-Richards Sandra
  • Khosse Ralf
  • Klyajn Kristian
  • Levitski Viktor
  • Umana Pablo
RU2761115C1
VARIANT CD3 BINDING DOMAINS AND THEIR USE IN COMBINATION THERAPY FOR TREATMENT OF DISEASES 2019
  • Bonvini, Etsio
  • Khuan, Lin
  • Lam, Chia-In Kao
  • Chichili, Gurunad Reddi
  • Alderson, Ralf Froman
  • Mur, Pol A.
  • Dzhonson, Lesli S.
RU2810222C2
IMMUNOCYTOKINES AND THEIR USE 2021
  • Wu Ellen
  • Wu Xiaoyun
  • Wakefield John
RU2818371C1
HER-2-DIRECTED ANTIGEN-BINDING MOLECULES CONTAINING 4-1BBL 2019
  • Ferrara Koller Claudia
  • Iuntilla Teemu Tapani
  • Klein Christian
  • Umana Pablo
  • Claus Christiana
RU2815451C2
ADAM9-BINDING MOLECULES AND THEIR APPLICATION METHODS 2017
  • Lu, Derik, T.
  • Skrajbner, Dzhuniper, A.
  • Barat, Bkhasvati
  • Didrich, Gundo
  • Dzhonson, Lesli, S.
  • Bonvini, Ezio
RU2783619C2

RU 2 744 176 C2

Authors

Dzhonson Lesli S.

Khuan Lin

Dates

2021-03-03Published

2009-12-17Filed