FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to chemical-pharmaceutical industry and represents a combination for treating a vasoconstriction involving disease, containing a compound of formula 
or a pharmaceutically acceptable salt of the compound and at least one compound possessing the PDE5-inhibitory properties, or its pharmaceutically acceptable salt for therapeutic application simultaneously, separately or over a period of time.
EFFECT: invention shows a synergetic effect when using the combination of such compounds in treating the vasoconstriction involving disease.
12 cl, 3 ex
