DIFFERENTIAL DIAGNOSTIC TECHNIQUE FOR ENDOGENOUS INTOXICATION Russian patent published in 2012 - IPC G01N33/49 

FIELD: medicine.

SUBSTANCE: differential diagnosing of endogenous intoxication is calculated by an endogenous intoxication coefficient (EIC) by formula: EIC=(SPEi:SPEk)(Ii:Ik) wherein SPEi is the sorption power of patient's erythrocyte, standard units, SPEk is the sorption power of control erythrocyte, standard units, Ii is the amount of patient's serum indican, mg %, Ik is the amount of control serum indican, mg %. If the EIC value is (M±2σ) 1.00+0.37, the absence of endogenous intoxication is stated. The gain of each of the equation component (SPEi, Ii) exceeding the control values separately, the EIC value in whole changes in min. 2 times as compared with the average control EIC values that testifies to the extraintestinal origin of endogenous intoxication. The combined gain of EICi and the level of patient's serum indican, the EIC values becomes more than 2.0 that enables stating the presence of endogenous intoxication of the colonic origin.

EFFECT: use of the given method enables determining the origin of endogenous intoxication that allows specifying the therapeutic approach to the patient, and thereby improving the clinical effectiveness.

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