NEW PREVENTIVE AND/OR THERAPEUTIC MEDICATION AGAINST DIABETIC NEUROPATHY Russian patent published in 2012 - IPC A61K31/5375 A61P3/10 A61P25/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: claimed is medication for prevention and/or treatment of diabetic neuropathy, which contains (+)2-[substituted-inden-7-yloxy)methyl]morpho-lyn (isomer of indeloxosin) or its pharmaceutically acceptable salt as the only active ingredient, its application for production of medication of the same purpose, respective method of treatment, its application for production of medication improving diabetic neuropathy pathophysiology, medication of the same purpose. It is demonstrated that invention ensures prevention and/or treatment of diabetic motor neuropathy (such as, malfunction with muscular weakness, including disability of independent walking), diabetic sensor neuropathy (such as paresthesia, including anomaly of vibration perception, allodynia, hypoesthesia such, as dumbness of extremities or sense of cold, or pain) or diabetic autonomic neuropathy (such as anomaly of stool: constipation or diarrhea, malfunction of urination, impotence, orthostatic hypotension, sudomotor dysfunction, anomalous variability of heart rate or slowing of evacuation of gastric contents).

EFFECT: invention ensures improvement of diabetic neuropathy pathophysiology: recovery of FGF-2, IGF-1 expression, reduction of rate of motor nerve conduction.

11 cl, 3 dwg, 3 tbl