FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to a combination of sigma-receptor ligand of formula (I) or its pharmaceutically acceptable salt, isomer or solvate, and a chemotherapeutic agent specified in a group formed by taxane, vincaalkaloids, platinum-based drugs and thalidomide. In formula 
(I), the radicals R1-R6 have the values specified in the patient claim, and n is specified in 2, 3 and 4.
EFFECT: declared combination can be used for preventing or treating pain caused by the above chemotherapeutic agents if administered simultaneously, separately or sequentially.
15 cl, 18 dwg, 4 ex
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