METHOD OF OBTAINING POLYALKYLENEGLYCOL ESTERS OF α-TOCOFEROL Russian patent published in 2012 - IPC C07D311/72 C08G65/26 C08G65/28 C08G65/331 C08G59/00 

Abstract RU 2467005 C1

FIELD: chemistry.

SUBSTANCE: invention relates to method of obtaining polyalkyleneglycol esters of α-tocoferol, applied in cosmetology, medicine and food industry. Method lies in interaction of α-tocoferol acetate with alkali, ethylene oxide or propylene oxide at temperature 100-175°C and pressure 1-5 atm. Process is carried out in two stages. At the first stage interaction of α-tocoferol with alkali and ethylene oxide or propylene oxide is performed. Oxide is used in amount 2-10 moles per a mole of α-tocoferol acetate. Obtained product is separated. At the second stage selected intermediate product is oxyakylated with ethylene and/or propylene oxide on presence of alkali.

EFFECT: invention makes it possible to obtain water-soluble polyalkyleneglycol esters of α-tocoferol, which do not contain inorganic admixtures.

2 cl, 2 tbl, 12 ex

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RU 2 467 005 C1

Authors

Kalinichenko Alla Nikolaevna

Danilenko Larisa Viktorovna

Bezulenko Valentina Nikolaevna

Fejzulova Rajsja Kurban-Galievna

Khromov Arkadij Valentinovich

Khan Ir Gvon

Dates

2012-11-20Published

2011-07-15Filed