FIELD: medicine.
SUBSTANCE: invention refers to fine stable emulsions of perfluoroorganic compounds (PFOC) which may be used as a base for preparing blood substitutes with gas transport function, as well as radiopaque contrast agents and mediums for organ preservation. The emulsion contains PFOC in the amount of 8÷80.0 wt %, an emulsifying and stabilising additive in the amount of 0.25÷8.0 wt % and a physiologically acceptable solution - the rest. The emulsifying and stabilising additive of the emulsion is presented by a non-ionic surfactant presenting mixed block copolymers of ethylene oxide and/or propylene oxide and/or polyalkylene glycol esters of tocopherol with polyglycidyl esters of fluorinated alcohols in relation 2:1 to 0.5:1, or the anionic surfactant presenting a monoester salt of dicarboxylic acid with aliphatic and/or pxyalkylated aliphatic and/or perfluorinated alcohols, or mixed said non-ionic and anionic surfactants in relation 39:1 to 1:39.
EFFECT: emulsion under the invention is aggregation- and sedimentation-stable; average particle size is no more than 200 nm; it is stored for a long period of time at room and high temperature with no substantial change in emulsion particle size.
11 cl, 24 tbl, 23 ex
