COMPOSITIONS, BASED ON 2-AMINO-1,3-RPOPANEDIOL COMPOUNDS Russian patent published in 2012 - IPC A61K31/133 A61K31/135 A61K31/12 A61K47/10 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to field of pharmaceutics and deals with pharmaceutical compositions based on organic concentrate for prevention and treatment of transplant rejection, treatment of autoimmune and allergic diseases, which includes 2-amino-1,3-propanediol compounds, selected from 2-amino-2-[4-(3-benzyloxyphenoxy)-2-chlorophenyl]propyl-1,3-propanediol, 2-amino-2-[4-(3-benzyloxyphenylthio)-2-chlophenyl]propyl-1,3-propanediol, 2-amino-4-(4-heptyloxyphenyl)-2-methyl-butanol and (2R)-2-amino-4-[3-(4-cyclohexyloxybutyl)-benzo[b]thien-6-yl]butan-1-ol in organic solvent, containing 0-78.9% (wt/vol) of ethanol in propylene glycol or 40-83% (wt/vol) of organic component in water, where organic component contains 10-90 wt/fractions of ethanol and 10-90 wt fractions of propylene glycol, methods of their obtaining and introduction.

EFFECT: obtaining pharmaceutical compositions, based on organic concentrate, for prevention and treatment of transplant rejection.

19 cl, 2 ex