METHOD FOR DETECTION OF IMMUNE RECONSTITUTION INFLAMMATORY DISEASE IN PATIENTS WITH DRUG-RESISTANT TUBERCULOSIS AND HIV INFECTION WITH UNDERLYING HIGH-ACTIVE ANTIRETROVIRAL THERAPY Russian patent published in 2012 - IPC A61K31/56 A61P37/00 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely phthisiology and infectious diseases, and may be used for detection of immune reconstitution inflammatory disease in the patients suffering drug-resistant tuberculosis and HIV infection. That is ensured by clinical assessment of the patient's state with underlying high-active antiretroviral therapy (HAART). If observing general loss of condition, temperature rise, progression of inflammatory process in the involved organs, prednisolone 0.5 mg/kg therapy is prescribed once a day for 10-12 days. The therapeutic course of prednisolone is followed by another clinical assessment, and if observing normalised temperature, regression of inflammatory process, general amelioration, the presence of immune reconstitution disease is stated.

EFFECT: use of the given method enables higher accuracy of detection of immune reconstitution disease in the patients with drug-resistant tuberculosis and HIV infection with underlying HAART.

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