NEW APPLICATION OF IL-1β COMPOUNDS Russian patent published in 2012 - IPC A61K39/395 A61P19/02 A61P37/02 

Abstract RU 2468817 C2

FIELD: medicine.

SUBSTANCE: presented group of inventions refers to medicine. What is presented is application of IL-1β binding antigen for producing a drug preparation for treating juvenile rheumatoid arthritis in a patient, containing at least one antigen-binding centre which involves a first domain having an amino acid sequence specified in SEQ ID NO:1, and a second domain having an amino acid sequence specified in SEQ ID NO:2. What is presented is a pharmaceutical composition containing said antibody in a combination with pharmaceutically acceptable excipients, solvents or carriers introduced parenterally.

EFFECT: presented group of inventions provides new application of IL-1β binding antibody for treating juvenile rheumatoid arthritis, particularly systemic idiopathtic juvenile rheumatoid arthritis in mammals, particularly in a human.

10 cl, 3 ex

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RU 2 468 817 C2

Authors

Lou Fil

Gram Germann

Jung Tomas

Rajt Timoti

Mundel Trevor

Dates

2012-12-10Published

2006-10-24Filed