FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to new sulphonamide derivatives of formula 
wherein fragment 
represents fragment 
and wherein X represents phenylene optionally substituted by one, two or three substitutes optionally specified in a group consisting of halogen, C1-6-alkyl, C1-6-alkoxy, halogen-C1-6-alkyl, halogen-C1-6-alkoxy, C1-6-alkylsulphonyl, C1-6-alkylthionyl, C1-6-alkylthio group, C1-6-alkylsulphonyl-C1-6-alkyl, C1-6-alkylthionyl-C1-6-alkyl, C1-6-alkylthio-C1-6-alkyl and C1-6-alkoxycarbonyl; Y represents pyridyl, pyrimidinyl or piperidyl which may be optionally substituted by one or two substitutes optionally specified in a group consisting of halogen, C1-6-alkoxy and C1-6-alkoxycarbonyl; or to its pharmaceutically acceptable salts. The sulphonamide derivatives of formula (I) represent chymase inhibitors and are applicable for preparing a pharmaceutical composition.
EFFECT: sulphonamide derivatives of formula (I) as chymase inhibitors.
8 cl, 36 ex
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