METHOD OF PRODUCING POLYPRENYL PHOSPHATES Russian patent published in 2013 - IPC C07F9/113 

FIELD: chemistry.

SUBSTANCE: present invention relates to an industrial method of producing polyprenyl phosphates having general structural formula:

, where each isoprene unit contains 5 carbon atoms, W denotes a ω-end isoprene unit, T denotes a trans-isoprene unit, C denotes a cis-isoprene unit, S denotes a 2,3-dihydroisoprene unit, a=0-10, b=0-39, c=0-1, a+b+c=4-40, X denotes a group of the formula OPO₃MM', wherein M and M' are identical or different and are a hydrogen cation or a monovalent inorganic or organic cation, or M and M' together are a divalent inorganic cation. The disclosed method involves phosphorylation of the corresponding polyprenol or a mixture of oligomer homologues of the given formula, where X is replaced with a hydroxy group, substituted by an ammonium salt of phosphoric acid in the presence of a condensing agent in a medium of a first aprotic organic solvent; and the reaction mixture is extracted and precipitated, while separating polyprenyl phosphate in form of mono- or di-substituted salts thereof with monovalent inorganic or organic cations or salts thereof with divalent inorganic cations.

EFFECT: novel, efficient and cheap method of producing polyprenyl phosphates.

20 cl, 16 ex