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(19)

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2 473 346

(13)

(51)

IPC

A61K31/695(2006-01-01)

A61K31/575(2006-01-01)

A61P1/16(2006-01-01)

(21) (22)

Application

2011129412/15, 2011-07-18

(24)

Start date

2011-07-18

(22)

Actual filing date

2011-07-18

(45)

Published

2013-01-27

(72)

Inventor

Aksenova Valentina AleksandrovnaKlevno Nadezhda IvanovnaBorzakova Svetlana NikolaevnaRejzis Ara Ruvimovna

(73)

Holder

Gosudarstvennoe Bjudzhetnoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Pervyj Moskovskij Gosudarstvennyj Meditsinskij Universitet Imeni I.M. Sechenova Ministerstva Zdravookhranenija I Sotsial'Nogo Razvitija Rossijskoj Federatsii Vpo Pervyj Mgmu Im. I.M. Sechenova Minzdravsotsrazvitija Rossii)Rossijskaja Federatsija, Ot Imeni Kotoroj Vystupaet Ministerstvo Zdravookhranenija I Sotsial'Nogo Razvitija Rossijskoj Federatsii Rossii)

METHOD OF TREATING DRUG-INDUCED LIVER INJURY IN CHILDREN SUFFERING FROM TUBERCULOSIS Russian patent published in 2013 - IPC A61K31/695 A61K31/575 A61P1/16

Abstract RU 2473346 C1

FIELD: medicine.

SUBSTANCE: declared invention refers to medicine. The anti-tuberculosis preparations are cancelled, while Ursosal 20 mg/kg is single administered per os, and Enterosgel 10-15 g for 3 days. Then, a dose of Ursosan is reduced to 12-15 mg/kg a day with underlying reinitiation of the anti-tuberculosis preparations, and the Ursosan therapy is continued until the ALT value appears to be below an upper limit of normal.

EFFECT: method under invention enables higher clinical effectiveness in the drug-induced liver injury in children.

1 tbl, 3 dwg, 2 ex

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RU 2 473 346 C1

Authors

Aksenova Valentina Aleksandrovna

Klevno Nadezhda Ivanovna

Borzakova Svetlana Nikolaevna

Rejzis Ara Ruvimovna

Dates

2013-01-27—Published

2011-07-18—Filed