INDANYL COMPOUNDS Russian patent published in 2013 - IPC C07C217/28 C07C229/34 C07D257/04 A61K31/24 A61K31/41 A61P3/14 A61P19/10 

FIELD: chemistry.

SUBSTANCE: in formula (I): , A is a single bond or a phenylene group which is substituted with R¹; R¹ is a methyl group; D is a single bond; R^2a and R^2b are identical or different and denote a hydrogen atom, a fluorine atom, a chlorine atom, a methyl group, a methoxy group, an ethoxy group or a trifluoromethyl group; R^3a and R^3b denote a hydrogen atom; R⁴ and R⁵ denote methyl groups, or R⁴ and R⁵ are bonded to each other to form an ethylene group; R⁶ is a methyl group or an ethyl group; m is an integer from 0 to 4; Z is a carboxy group. The invention also relates to a pharmaceutical composition containing said compounds, use of said compounds to produce a medicinal agent for treating or preventing disorders associated with abnormal bone or mineral homeossatis, such as hypoparathyroidism and osteoporosis, and a method of improving bone metabolism.

EFFECT: high activity of the calcium receptor antagonist.

15 cl, 78 tbl, 85 ex